Sunday, January 8, 2012

Diagnose It

A 40 year female having swelling of right foot since 11 years. The nodules on the swelling were painful, drained periodically and made weight bearing difficult. She had received courses of antibiotics with partial responses. What is the diagnosis?





a) Tuberculous osteomyelitis
b) Blastomycosis
c) Madura foot
d) Histoplasmosis
e) Leishmaniasis



Answer is c) Madura foot.

Examination showed soft-tissue swelling, multiple red, boggy, subcutaneous nodules, and draining sinus tracts. Culture of a specimen from a punch biopsy failed to grow any organisms. However, histologic analysis revealed whitish-yellow granules and the presence of non–acid-fast filamentous bacteria consistent with Madura foot. This condition can be caused by either filamentous actinobacteria (actinomycotic mycetoma) or true fungi (eumycotic mycetoma). The pale color of the granules combined with the fact that the patient was from Mexico, where most mycetomas are caused by actinomadura species, made actinomycotic mycetoma the more likely diagnosis. Magnetic resonance imaging of the foot was performed, and the scan obtained indicated possible osteomyelitis.

Read more about madura foot HERE

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